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Case Report
Unique case of cutaneous Cunninghamella infection in an immunocompromised patient
1 Saba University School of Medicine, 27 Jackson Rd., Suite #300, Devens, MA, USA
2 The Jewish Hospital Department of Surgical Oncology, 4777 E Galbraith Rd., Cincinnati, OH, USA
3 The Jewish Hospital Department of Infectious Disease, 4777 E Galbraith Rd., Cincinnati, OH, USA
Address correspondence to:
Mauricio Portillo
Saba University School of Medicine, 27 Jackson Rd., Suite #300, Devens, MA,
USA
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Article ID: 100003D02MP2021
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Portillo M, Allamaneni S, Goodman R. Unique case of cutaneous Cunninghamella infection in an immunocompromised patient. Edorium J Dermatol 2021;3:100003D02MP2021.ABSTRACT
Cunninghamella species are an extremely rare cause of fungal infections. The usual mode of transmission is through inhalation; however, rare cases of cutaneous spread have been reported. The objective of this clinical case report is to highlight the uniqueness of which the patient acquired the infection, the progression, and control of it. A 57-year-old male with chronic lymphocytic leukemia was found to have an abscess next to his peripherally inserted central catheter (PICC) line. The abscess culture grew back Cunninghamella and was debrided and treated with isavuconazonium sulfate. The fungal infection was controlled and the total timeframe took 28 days. Rapid recognition and prompt treatment demonstrate the prevention of rapidly progressive angioinvasion and further systemic complications. This case also proves that isavuconazonium sulfate may be appropriate in controlling the spread of Cunninghamella species.
Keywords: Case report, Cutaneous infection, Cunninghamella, Immunosuppression
SUPPORTING INFORMATION
Author Contributions
Mauricio Portillo - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Shyam Allamaneni - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Richard Goodman - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source Of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Mauricio Portillo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
